Search on: ALZHEIMER DISEASE 
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Descriptor English:   Alzheimer Disease 
Descriptor Spanish:   Enfermedad de Alzheimer 
Descriptor Portuguese:   Doença de Alzheimer 
Synonyms English:   Dementia, Senile
Acute Confusional Senile Dementia
Dementia, Alzheimer Type
Presenile Alzheimer Dementia
Senile Dementia, Alzheimer Type  
Tree Number:   C10.228.140.380.100
C10.574.945.249
F03.615.400.100
Definition English:   A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57) 
See Related English:   Amyloid beta-Peptides
Amyloid beta-Protein Precursor
Aphasia, Primary Progressive
Cerebral Amyloid Angiopathy
Kluver-Bucy Syndrome
Neurofilament Proteins
tau Proteins
 
History Note English:   1998(1963); for DEMENTIA, PRESENILE and DEMENTIA, PRIMARY DEGENERATIVE SENILE use DEMENTIA 1981-1999; for DEMENTIA SENILE use DEMENTIA 1966-1999 
Allowable Qualifiers English:  
BL blood CF cerebrospinal fluid
CI chemically induced CL classification
CO complications CN congenital
DI diagnosis DH diet therapy
DT drug therapy EC economics
EM embryology EN enzymology
EP epidemiology EH ethnology
ET etiology GE genetics
HI history IM immunology
ME metabolism MI microbiology
MO mortality NU nursing
PS parasitology PA pathology
PP physiopathology PC prevention & control
PX psychology RA radiography
RI radionuclide imaging RT radiotherapy
RH rehabilitation SU surgery
TH therapy US ultrasonography
UR urine VE veterinary
VI virology  
Record Number:   545 
Unique Identifier:   D000544 

Occurrence in VHL:
 

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